화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2008년 가을 (10/09 ~ 10/10, 일산킨텍스)
권호 33권 2호
발표분야 의료용 고분자 부문위원회
제목 Self-Crosslinking Injectable Hydrogels Containing BMP-2 Releasing Gelatin Microspheres
초록 A new microsphere-hydrogel composite, composed of BMP-2-loaded gelatin microspheres and self-crosslinking poly(amino acid)-based hydrogels, was developed for a bone-regenerative matrix. The self-crosslinking hydrogel can act as an injectable depot at lesion sites, and incorporated gelatin microspheres, prepared by precision particle fabrication technology, can control the release rate of loaded BMP-2. Microsphere-hydrogel composites described in this work can diversify the class of injectable hydrogel systems for bone tissue engineering. Acknowledgement. This research was supported by a grant (code #: 08K1501-01110) from 'Center for Nanostructured Materials Technology' under '21st Century Frontier R&D Programs' of the Ministry of Education, Science and Technology, Korea.
저자 이홍재1, 김경자1, 최형수2, 김계균2, 이상천1
소속 1요업(세라믹)기술원, 2Univ. of Illinois
키워드 microsphere-hydrogel composite; self-crosslinking; injectable hydrogel; BMP-2 loaded gelatin microsphere; BMP release
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