화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터)
권호 44권 2호
발표분야 고분자구조 및 물성
제목 pH-Responsive Poly(acrylic acid) Modified Mesoporous Silica Nanoparticles for Releasing Guest Molecules
초록 We synthesized poly(acrylic acid) modified mesoporous silica nanoparticles(MSNs) to prepare effective pH-responsive nanocarrier. (3-Trimethoxysilyl)propyl methacrylate(TMSPM) functionalized surface was prepared by using post-grafting method, then free-radical polymerization of acrylic acid(AA) was proceeded using potassium persulfate as an initiator. The structure and morphology of the modified nanoparticles were characterized by X-ray diffraction, FT-IR, DLS, SEM, TEM, and N2 adsorption-desorption analysis. The prepared particles have well-ordered mesoporous structure and large pore size and pore volume that is proper as a carrier for guest particles. We studied on the controlled releasing of Rhodamine B(RhB) as a guest molecule. The guest molecules-incorporated MSNs showed different releasing rate of RhB under various pH conditions(pH 7.4, 5.6, 4.0). It demonstrated that our current materials have possibilities to be utilized in catalytic applications, drug delivery and so on.
저자 공정원, 하창식, 박성수
소속 부산대
키워드 mesoporous silica nanoparticles; drug delivery; poly(acrylic acid); pH-responsive guest molecules release
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