화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터)
권호 44권 2호
발표분야 의료용 고분자 부문위원회 II
제목 Antibacterial and Strongly Adhesive Complex Gel from Biocompatible PHEA-EDA and Tannic Acid
초록 A polyaspartamide derivative containing both hydroxyl and amine pendant, PHEA-EDA, was prepared from polysuccinimide via a controlled ring-opening aminolysis reaction using ethanolamine(EA) and ethylenediamine(EDA). Upon mixing tannic acid (TA) with PHEA-EDA in aqueous solution, viscous complex gel or precipitates was resulted, where the complexation behavior is influenced by the composition, pH, and temperature. TA, a plant-derived polyphenolic compound, can function not only as a gelator via strong non-covalent interaction but an effective adhesion promoter. The adhesive performance of the complex gels in varying conditions, obtained by lap shear test upon glass and acrylic plastic as the substrate, was discussed together with the antimicrobial property. Strong and multiple hydrogen-bonding interactions between TA and biocompatible polyaspartamides seem to be responsible for producing these complex gels, which are potentially useful as a novel biomedical soft adhesive.
저자 란윈눡홍랜, 당궉닷, 문종렬, 왕보, 김지흥
소속 성균관대
키워드 tannic acid; hydrogen-bonding; polyaspartamide; adhesive hydrogel; antibacterial
E-Mail