화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 기능성 고분자
제목 Enhanced modified Agarose hydrogels with Resveratrol for Retinal Pigment Epithelial cells regeneration
초록 Agarose (Agr) is a purified linear galactan hydrocolloid isolated from agar or agar-bearing marine algae. It is biocompatible and it has temperature sensitivity to solidify at body temperature and in liquid state at high temperature. Resveratrol (RSV) is a polyphenol phytoalexin, which found in the skin of berries and peanuts. It has anti-oxidant, anti-inflammatory, anti-epithelial-mesenchymal transition and anti-proliferative roles through sirtuin. Cylindrical RSV/Agr hydrogels were prepared with 0, 5, 10, 20, 30 and 50w% RSV with 3w% Agarose. The characteristics of the RSV/Agr hydrogel were analyzed by Fourier transform infrared spectroscopy (FT-IR), porosity and water uptake, compressive strength and scanning electron microscopy (SEM). As a result, the higher the content, the denser and more numerous pores were formed. In future, the in vitro test using rabbit retinal pigment epithelial cells will be studied.
저자 신명은, 김원경, 김진수, 강길선
소속 전북대
키워드 Agarose; hydrogel; scaffold; RPEc; regeneration
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