화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 기능성 고분자
제목 Evaluation of hyaluronic acid loaded agar hydrogel for chondrocyte regeneration
초록 Hyaluronic acid is gaining popularity as a biomaterial scaffold in tissue engineering field due to its biocompatibility and its presence in the extracellular matrix of tissues. However, it needs a specific treatment to crosslink the material in order to improve its mechanical properties. Below 40℃, Agar forms a non-cytotoxic hydrogels and is often used as a support for the tri-dimensional culture of human cells. For this reason it can be utilized to reproduce the extracellular matrix (ECM) in the hydrogel and to support the proliferation and differentiation of chondrocytes for cartilage regeneration. In this study, agar (2wt%) solutions with the addition of 0, 0.25, 0.5, 0.75, 1 wt% of hyaluronic acid were prepared to study the effect of hyaluronic acid on chondrocytes. The scaffolds were characterizations by FT-IR, compressive strength, SEM for porosity, then the cell proliferation was evaluated by MTT and Confocal.
저자 김진수, 강길선
소속 전북대
키워드 hydrogel; chondrocyte; regeneration
E-Mail