화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 의료용 고분자 부문위원회 I (영어발표)
제목 Polymers and Polymerization for Living Cell Coating
초록 The first attempt of living cells coating has been conducted by organic polymers through layer-by-layer methods. To achieve more practical demonstration, coating materials shifted from organic polymers to inorganic materials. The polymers have been used as catalytic templates for biomimetic synthesis of inorganic materials. Furthermore, it was developed a cytocompatible surface-initiated, atom transfer radical polymerization (SI-ATRP) method for grafting polymers from living cells with use of polydopamine priming. Modulation of cell-surface properties and cellular activities was demonstrated, along with post-functionalibility of polymer coats. Considering a plethora of functional and structural variations in synthetic polymers, grafting polymers from (or to) cell surfaces would generate multifunctional cellular hybrids for many biotechnological and biomedical applications, not to mention providing an advanced tool for chemically manipulating the cells.
저자 양성호
소속 한국교원대
키워드 Polymerization; ATRP; Cell coating
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