|학술대회||2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU))|
|제목||Fimasartan potassium trihydrate을 함유한 ODF의 제조 및 평가|
|초록||Fimasartan potassium trihydrate a Hypertension and heart failure medicine, was incorporated in orally disintegrating film (ODF) and evaluated. Polyvinyl Alcohol (PVA) and Pullan is a polymer compound obtained by saponifying polyvinyl acetate with alkali, acid, ammonia water or the like, and is used for producing an aqueous solution film. Polyethylene Glycol and Glycerol is a polymer used to cause cell fusion as a plasticizer, has many advantages such as dissolving the drug, permeability, stability and unchanging. Tween 80 is a highly hydrophilic surfactant, and is used as an emulsifier. N-Methyl-2-pyrrolidone (NMP) is an organic compound consisting of a 5-membered lactam.
Therefore, we decided to select 'D' as the optimal recipe for producing ODF containing the following components.
|저자||박지윤, 김도훈, 염유진, 박동현, 김영일|
|키워드||oral film; flurbiprofen; polyvinyl alcohol; content evaluation|