화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO))
권호 22권 1호
발표분야 생체재료_포스터
제목 Gellan Gum/Silk Fibroin Hydrogel Scaffolds for Cartilage Regeneration
초록 Recently, in tissue engineeringGellan gum as a polysaccharide composed of glucose, glutaric acid, and rhamnose is proposed as a substitute forcartilage regeneration applications. Silk Fibroin has biocompatibility, biodegradability and excellent mechanical properties. In this work, to confirm the effect of silk fibroin on cartilage regeneration, hydrogel scaffold was prepared by using 2wt% silk fibroin(SF)/ 2wt% Gelln gum(GG) at weight ratio of 100/0, 70/30, 50/50. The characterizations of scaffolds were implemented by FT-IR, Compressive strength, porosity, and SEM. Cell proliferation and gene expression were evaluated by MTT, Bio-SEM, RT-PCR. As a result, SF50/GG50 scaffold was confirmed as excellent scaffoldfor cartilage tissue regeneration. This research was supported by a grant of the Korea Health Technology R&D Project through KHIDI (HI15C2996 ).
저자 박종호, 신은영, 백종선, 강길선
소속 전북대
키워드 hydrogel; silk fibroin
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