화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center))
권호 21권 1호
발표분야 고분자
제목 Near infrared light-responsive core cross-linked polymeric micelles of poly(ethylene oxide)-b-poly(glycidyl methacrylate) utilizing diselenide cross-linker
초록 In this study, near infrared light-responsive core cross-linked micelles of poly(ethylene oxide)-b-poly(glycidyl methacrylate) (PEO-b-PGMA) block copolymers were prepared by a diselenide cross-linker using click chemistry. Diblock copolymers of PEO-b-PGMA were synthesized by the RAFT polymerization and subsequently were functionalized with azide groups. The micelles of azido functional PEO-b-PGMA-(N3) were cross-linked by dipropargyl 3,3’diselanedyldipropionate in the presence of copper(II) sulfate pentahydrate and sodium ascorbate using alkyne-azide click reaction. The block copolymers and cross-linked micelle were characterized by using gel permeation chromatography, fourier-transform infrared spectroscopy, 1H nuclear magnetic resonance, and dynamic light scattering analysis. The core cross-liked micelle presented a stable structure and cleavage of diselenium bond occurred in the presence of reactive oxygen species under near infrared light irradiation.
저자 서용성, 임권택, Salma Sabrina Aufar, Cuong M.Q. Le
소속 부경대
키워드 click chemistry; RAFT polymerization; core cross-linked micelles; NIR responsive
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