||Platinum is an anti-corrosive, easily moldable noble metal performing good catalytic activities in a variety of chemical reactions. However, the high cost of platinum limits large-scale usage in industry as a catalyst. Although, platinum can widely be used in medical devices as its required amount for each device is very small. Furthermore, the anti-corrosion property in long-term storage and the excellent bio-compatibility are advantages of platinum. However, wettability of platinum surface particularly for blood-wettability in many platinum-coated medical devices has been a problem. In this study, we report a novel molecule called sulfo-alkanethiols that provide good blood-philicity on surface of platinum surfaces. The sulfonate group allows blood-philicity, and the thiol group makes anchor the molecule on platinum surfaces. After surface modifications, blood contact angle of the modified surfaces exhibited less than 10°, indicating that these surfaces are converted to be highly blood-philic surfaces. It is expected that this platinum surface modification might enhance performance of the platinum surfaced medical devices such as guide-wire insertion in the presence of blood overflow.