화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.134, No.21, 8778-8781, 2012
Stereoselective Intermolecular Allylic C-H Trifluoroacetoxylation of Functionalized Alkenes
Pd-catalyzed allylic C-H trifluoroacetoxylation of substituted alkenes was performed using PhI(OCOCF3)(2) as the oxidant and acyloxy source. Trifluoroacetoxylation of monosubstituted cyclopentenes and cyclohexenes proceeds with excellent regio- and diastereoselectivity. Studies with one of the possible (eta(3)-allyl)Pd(II) intermediates suggest that the reaction proceeds via stereoselective formation of Pd(IV) intermediates and subsequent stereo- and regioselective reductive elimination of the product.