화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.130, No.15, 5048-5048, 2008
Synthesis of arylallenes by palladium-catalyzed retro-propargylation of homopropargyl alcohols
Treatment of tertiary homopropargyl alcohol with aryl halide under palladium catalysis provided arylallenes regioselectively. The reaction includes retropropargylation, which proceeds in a concerted fashion via a cyclic transition state and transfers the stereochemistry of homopropargyl alcohols through C-C bond cleavage. The present method enables the use of homopropargyl alcohols as allenylmetal equivalents.