화학공학소재연구정보센터
Journal of Applied Polymer Science, Vol.111, No.5, 2607-2615, 2009
Synthesis of Thermosensitive Glycopolymers Containing D-Glucose Residue: Copolymers with N-isopropylacrylamide
A new glycomonomer, 3-acrylamido-3-deoxy-1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose, was synthesized from D-glucose. This monomer was homo-polymerized and copolymerized with N-isopropylacrylamide in different compositions by free-radical polymerization. The composition of the copolymer was determined with H-1-NMR spectroscopy. On acid hydrolysis, water-soluble deprotected copolymers were obtained. The protected and deprotected copolymers showed a sharp cloud-point temperature. A linear correlation was obtained between the lower critical solution temperatures and the concentration of glycomonomer in the copolymers (C) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 111: 2607-2615, 2009