Advanced Materials, Vol.20, No.1, 37-37, 2008
Fmoc-Diphenylalanine self assembles to a hydrogel via a novel architecture based on pi-pi interlocked beta-sheets
The self assembly of peptide hydrogelators that carry aromatic substituents can be modeled by a novel nanocylindrical architecture. The proposed model suggests that the nanocylinders are formed by anti-parallel beta-sheets interlocked by the pi-stacking interactions of fluorenyl groups and phenyl rings. This explanation is consistent with the structures observed in TEM and the data obtained by a variety of spectroscopic techniques.