화학공학소재연구정보센터
Korean Chemical Engineering Research, Vol.46, No.4, 752-755, August, 2008
SBA-15 실리카에 고정화된 ruthenium 촉매를 사용한 Microwave하에서의 비대칭 수소 전달반응
Microwave-mediated Asymmetric Hydrogen Transfer by SBA-15-supported Ruthenium Catalyst
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초록
메조포러스 SBA-15 silica와 (1R,2R)-N-(trimethoxysilylpropyl-N-sulfonyl)-1,2-cyclohaxanediamine 또는 (1R,2R)-N-(trimethoxysilylpropyl- N-sulfonyl)-1,2-diphenylethylenediamine과의 반응을 통하여 메조포러스 silica SBA-15-supported TsCHDA와 TsDPEN가 각각 제조되어졌다. SBA-15-supported TsCHDA로부터 얻어진 ruthenium complex들은 microwave하에서의 케톤의 비대칭 수소 전달반응에서 우수한 촉매능과 만족할 만한 거울상 입체선택도를 주었다. 이 불균일상 SBA-15-supported ruthenium 촉매는 사용이 용이하게 안정할 뿐 만 아니라, 재사용 할 수 있었다. 비대칭 수소전달반응을 위한 microwave를 사용한 효율적인 공정이 개발되었다.
Mesoporous SBA-15 silica-supported TsCHDA and TsDPEN ligands have been prepared by reaction of SBA-15 silica with (1R,2R)- N-(trimethoxysilylpropyl-N-sulfonyl)-1,2-cyclohaxanediamine or (1R,2R)- N-(trimethoxysilylpropyl-N-sulfonyl)-1,2-diphenylethylenediamine-1,2- diphenylethylenediamine, respectively. The Ru complexes exhibited excellent catalytic activity and satisfactory enantioselectivity in the asymmetric hydrogen transfer of ketones under microwave conditions. The heterogeneous Ru catalyst was reusable as well as air-stable to allow easy use. Microwave-assisted efficient procedure has been developed for asymmetric hydrogen transfer.
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