화학공학소재연구정보센터
Biochemical and Biophysical Research Communications, Vol.272, No.2, 531-538, 2000
Determination of genes involved in the process of implantation: Application of GeneChip to scan 6500 genes
Using the high-density arrays of oligonucleotides (GeneChip) technology, the expression of uterine genes was examined before and after conceptus implantation in mice, Of the 6500 genes analyzed, levels of 399 gene expressions changed; 192 genes increased levels of expression while the remaining 207 genes declined, The findings suggest that both gene activation and deactivation (suppression) are required for successful implantation.