Chemistry Letters, Vol.31, No.9, 908-909, 2002
Cyclohexynes. Generation from iodonium salts and regioselective reaction with nucleophile
Cyclohexynes are effectively generated by treatment of cyclohex-1-enyliodonium salts with a mild base such as acetate and fluoride ion in chloroform. Regioselectivity of the nucleophilic addition of acetate ion to cyclohexynes depends on the 4-substituent.