Chemical Engineering Science, Vol.49, No.4, 541-547, 1994
Simplified Analysis of Chromatographic-Column Dynamics
A simplified analysis of chromatographic-column dynamics based on a similarity equation (found experimentally) for outlet chromatograms of size-exclusion columns is developed. A theoretical explanation of the similarity equations is developed in the case of a convection-diffusion model. A criterion for validating the similarity results is proposed. As a corollary of the above analysis, an integral method for evaluating the variance is proposed.