Thermochimica Acta, Vol.400, No.1-2, 213-219, 2003
Importance of heat capacity determination in homogeneous nucleation: application to progesterone
Progesterone is known to exist under different crystallographic forms in the solid state. The thermodynamic stable form (1), melts at 129.2degreesC (402.35 K) under atmospheric pressure. After melting and cooling a metastable form (H) can be obtained which melts at 122 degreesC (395.15 K). This uncommon behaviour can be explained with the theory of nucleation, only if heat capacity of the different forms are known.