Thermal Decomposition Products of Phthalates with Poly(vinyl chloride) and Their Mutagenicity

Katsuhiko Saido; Hiroyuki Taguchi; Satoru Yada; Yumiko Ishihara; Takeshi Kuroki; In-Jae Ryu; Seon-Yong Chung

Macromolecular Research, Vol.11, No.3, 178-182, June, 2003

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Thermal Decomposition Products of Phthalates with Poly(vinyl chloride) and Their Mutagenicity

Katsuhiko Saido^†, Hiroyuki Taguchi, Satoru Yada, Yumiko Ishihara¹, Takeshi Kuroki¹, In-Jae Ryu², and Seon-Yong Chung²

College of Pharmacy, NIHON University, 7-7-1 Narashinodai, Funabashi-shi, Chiba 274-8555, Japan
¹Polymer Decomposition Laboratory Co., Ltd., 2-12-7 Aoshima, Miyazaki-shi, Miyazaki 889-2162, Japan
²College of Engineering, Chonnam National University, 300 Yongbong-Dong, Buk-ku, Gwangju 500-757, Korea

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The thermal decomposition of phthalate alone and with poly(vinyl chloride) (PVC) was carried out under a nitrogen atmosphere in a 4-necked separable flask. The thermal decomposition of phthalate in the presence of PVC began at 150 °, about 100 ℃ lower than the decomposition of phthalate alone. The formation of octyl chloride indicated an interaction reaction between phthalate and PVC. From the analysis of the composition of commercially plasticized PVC sheet (film and board), the phthalates (dibutyl phthalate, dihexyl phthalate) and di(2-ethylhexyl) phthalate), 2-ethyl-1-hexanol, phthalic anhydride, and 2-ethylhexyl hydrogen phthalate were identified. The mutagenicities of these decomposition products were higher than those of phthalic diesters (phthalates).

Keywords:di(2-ethylhexyl) phthalate;dioctylphthalate;poly(vinyl chloride);thermal decomposition;mutagenicity

[References]

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[Referenced By]

[1] Makino T, Jpn. Plast., 54(1), 31 (2003)

[2] Cooray BB, Scott G, Eur. Polym. J., 16, 169 (1980)

[3] Harris CA, Henttu P, Parker MG, Sumpter JP, Environ. Health Persp., 105, 802 (1997)

[4] Abbas KB,Sovik EM, J. Appl. Polym. Sci., 17, 3567 (1977)

[5] Uemichi Y, Takuma K, Sugioka M, Kanazuka T, Bull. Chem. Soc. Jpn., 64, 735 (1991)

[6] Rogestedt M, Hjertberg T, Macromolecules, 25, 6332 (1992)

[7] McNeil Ic, Memetea L, Polym. Degrad. Stabil., 43, 9 (1994)

[8] Gokcel HI, Balkose D, Adv. Polym. Technol., 17(1), 63 (1998)

[9] Niino T, Ishibashi T, Itho T, Sakai S, Ishiwara H, Yamada T, Onodera S, J. Health Sci., 47(3), 318 (2001)

[10] Wine RN, Li LH, Barnes LH, Gulati DK, Chapin RE, Environ. Health Persp., 105, 102 (1997)

[11] DeBoer TJ, Backer HJ, Reac. Trav. Chim., 73, 229 (1954)

[12] Yahagi T, Nagao M, Seino Y, Matsushima T, Sugimura T, Okada M, Mutat. Res., 48, 121 (1977)

[13] Lum KK, Smith GG, Int. J. Chem. Kinet., 1, 401 (1969)

[14] Saido K, Watabe T, Motohashi S, Kuroki T, Ikemura T, Kirisawa M, Eisei Kagaku, 27, 16 (1981)

[15] Singh AR, Lawrence WH, Autian J, J. Pharm. Sci., 61, 51 (1972)

[16] Nakamura Y, Tomita I, Jpn. Toxicol. Environ. Health, 33, 71 (1987)

[17] Hayashi M, Hayashi S, Bull. OSAKA-FU Pub. Health Lab., 7, 46 (1969)