Journal of Chemical and Engineering Data, Vol.66, No.3, 1508-1514, 2021
Solubility Determination and Thermodynamic Correlation of 2-Ethoxybenzamide in 12 Pure Solvents from 288.15 to 328.15 K
The solubility of 2-ethoxybenzamide was measured in 12 pure solvents, namely, 2-propanol, 1-butanol, 2-butanol, 1-pentanol, ethyl formate, methyl acetate, propyl acetate, n-butyl acetate, N, N-dimethylformamide, 1,4-dioxane, acetone, and 2-butanone from 288.15 to 328.15 K at atmospheric pressure by the gravimetric method. The solubility of 2-ethoxybenzamide in all 12 pure solvents increases monotonically with temperature. The highest solubility value was found in N, N-dimethylformamide, while the lowest one was found in n-butyl acetate. Among various investigated influence factors such as solvent polarity, hydrogen bond donor propensity, hydrogen bond acceptor propensity, and cohesive energy density, the polarity of solvent was found to play a major role in 2-ethoxybenzamide solubilities. Furthermore, the lambda h equation, van't Hoff equation, and modified Apelblat equation were employed to correlate the solubility data of 2-ethoxybenzamide, where the modified Apelblat equation displayed the best fitting performance.