화학공학소재연구정보센터
Chemistry Letters, Vol.49, No.11, 1309-1311, 2020
Degradation of Unprotected Aldohexonic Acids to Aldopentoses Promoted by Light and Oxygen
Herein reported is a photoredox-catalyzed oxidative degradation reaction of unprotected aldohexonic acids, which are shortened by one-carbon to the corresponding aldopentoses. Oxygen including aerial oxygen is used as a terminal oxidant. The mild reaction conditions permit even disaccharides to successfully undergo the degradation reaction with the glycosidic bond remaining intact. Quinic acid is also converted to a useful chiral synthetic intermediate.