화학공학소재연구정보센터
Chemistry Letters, Vol.48, No.10, 1209-1212, 2019
C-60 Fullerene with Tetraethylene Glycols as a Well-defined Soluble Building Block and Saccharide-conjugation Producing PDT Photosensitizer
Tetraethylene glycol (TEG)-conjugated (C-60-I-h)[5,6]fullerene (TEG-C-60) was synthesized as a soluble molecular building block generating C-60-based conjugates with advanced properties. The improved solubility allowed the glycosylation reaction with TEG-C-60 using a Lewis acid in chloroform at low temperature. The resultant glycoconjugated TEG-C-60 was characterized in terms of water solubility, ability to generate reactive oxygen species (ROS), and photodynamic activity.