화학공학소재연구정보센터
Chemical Engineering & Technology, Vol.42, No.10, 1985-1995, 2019
Equipment and Separation Units for Flow Chemistry Applications and Process Development
Process development and small-scale production gets more and more important in fine chemistry and pharmaceutical production. An equipment toolbox assists process synthesis presented in this contribution. A microfluidic calorimeter can measure kinetic and thermodynamic reaction data with commercial plate reactors. A tubular reactor coiled with 90 degrees bends allows for long residence time with low axial dispersion, also known as coiled flow inverter (CFI). A similar setup is used for continuous-flow cooling crystallization. Small-scale columns with rotating internals are employed for distillation and liquid-liquid extraction. Main emphasis will be put on automation and scale-up in future steps.