화학공학소재연구정보센터
Macromolecular Research, Vol.26, No.12, 1129-1134, December, 2018
Facile Synthesis of Surfactant-Free Au Decorated Hollow Silica Nanoparticles for Photothermal Applications
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We report herein a novel surfactant-free synthetic approach for hollow silica nanoparticles (HSN) loaded with Au nanocomposites (Au-HSN) to enhance photothermal properties. Transmission electron microscopy and elemental analysis confirmed the uniform HSN of Au nanoparticles. UV-vis spectroscopy and Fourier transform infrared spectroscopy were performed to demonstrate the dopamine (DA)-hyaluronate (HA) coating on Au-HSN. These nanocomposites dramatically increased up to 48 °C within few seconds under near-infrared irradiation. In addition, these Au-HSN/DA-HA nanoparticles showed the excellent endocytosis against cancer cells without any cytotoxicity. Therefore, it could be a powerful nanocarrier for tumor targeting and photothermal therapy applications.
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