화학공학소재연구정보센터
Journal of Chemical and Engineering Data, Vol.63, No.8, 2999-3007, 2018
Differential Partitioning of Bioantioxidants in Edible Oil-Water and Octanol-Water Systems: Linear Free Energy Relationships
Partition coefficients, P-w(o), of antioxidants (AOs) between edible oils and water are scarce in the literature, despite that AOs are widely used to control lipid oxidation and the oxidative stress in cells. P-w(o) values have a great importance to predict the efficiency and distribution of bioactives at different levels of biological organization from binary oil-water systems to living cells. Here, we determined the partition coefficients, P-w(o), of four series of potent, natural AOs of increasing lipophilicity between vegetable oils (olive, soybean, and corn) and water and, for the sake of comparison, between octanol-water, P-w(OCT). Results indicate that the contribution of the -CH2 groups to the overall lipophilicity of the AO is the same irrespective of the oil employed. The P-w(o) values were compared with P-w(OCT) values, and linear relationships were obtained for each series of AOs. Results indicate that, in general, P-w(o) values cannot be predicted from the P-w(OCT) values, making necessary to determine the P-w(o) values for each oil and antioxidant.