화학공학소재연구정보센터
Chemical Reviews, Vol.118, No.14, 6893-6923, 2018
Cancer Metabolism: Current Understanding and Therapies
Dysregulation of cancer cell metabolism contributes to abnormal cell growth, the biological end point of cancer. We review here numerous affected oncogenes and metabolic pathways common in cancer and how they contribute to cancer pathogenesis and malignancy. This review also discusses various pharmacological manipulations that take advantage of these metabolic abnormalities and the current targeted therapies that have arisen from this research.