Chemistry Letters, Vol.46, No.6, 821-823, 2017
A Practical Screening Strategy of Arsenic Ligands for a Transition-metal-catalyzed Reaction
Organoarsenic ligands were synthesized via a safe and easy procedure, superior to the conventional synthetic methodologies. Diiodophenylarsine was prepared in situ, and was readily converted to diarylphenylarsines. Pd-catalyzed Mizoroki-Heck reaction was investigated using the obtained arsenic ligands. It was found that bulky and electron-donating ligands were effective for the reaction, meaning that the success in the screening of arsenic ligand structures was based on the present facile strategy.