화학공학소재연구정보센터
Molecular Crystals and Liquid Crystals, Vol.607, No.1, 215-222, 2015
Synthesis and Crystal Structure Characterization of (1R,2R,3R,5S)-3-(3-chlorophenyl)-1-hydroxy-2-methyl-6-phenyl-8-oxa-6-aza bicyclo[3.2.1]octan-7-one
The title compound, (1R,2R,3R,5S)-3-(3-chlorophenyl)-1-hydroxy-2-methyl-6-phenyl-8-oxa-6-azabicyclo[3.2.1]octan-7-one, was synthesized and characterized by H-1 and C-13 NMR and HRMS spectroscopy. Its absolute molecular configuration was investigated by X-ray crystallography. The crystal structure analysis revealed that the structure exhibits intermolecular hydrogen bonds of the type O-H horizontal ellipsis O. The methyl group and chlorophenyl group are located in the cis configuration. The conformation is stabilized by weak intermolecular C-H... O interactions.