Molecular Crystals and Liquid Crystals, Vol.536, 17-23, 2011
Influence of Surface-Active Stabilizers on Porphyrin - Gold Nanoparticles Absorption and Fluorescence
Systems consisting of (HP) hematoporphyrin- and (PVP) polyvinylpyrrolidone-coated gold nanoparticles (GNP) that proved their efficiency as photosensitizer in in vitro experiments were studied by spectral-photometric and spectral-fluorescent methods. The spectral manifestation of the interaction between HP- and PVP-coated nanoparticles mainly corresponds to the PVP-HP interaction. The optical absorption and fluorescence spectra of the HP-PVP solutions in acidic, neutral, and basic media were investigated. The spectral shifts and changes in the luminescence intensity corresponding to the binding of HP to PVP were measured. PVP was found to reduce the aggregation of HP, and the efficiency of this process increases with pH.