화학공학소재연구정보센터
Macromolecules, Vol.49, No.5, 1712-1721, 2016
Polymer Functional Nanodiamonds by Light-Induced Ligation
A light-triggered strategy to functionalize nanodiamonds (NDs) with well-defined functional polymers is presented. The employed grafting approach is based on o-methylbenzaldehydes, which upon UV irradiation form o-quinodimethanes that undergo Diels-Alder reactions with dienophiles. A series of well-defined maleimide end-group functional polymers, i.e., poly(styrene) (M-n = 5800 g mol(-1); D = 1.2), poly(N-isopropylacrylamide) (M-n = 5800 g mol(-1), D = 1.2), and poly(-(2',3',4',6'-tetra-O-acetyl-alpha-D-mannosyloxy)ethyl methacrylate) (M-n = 24 300, 39 000, and 58 800 g mol(-1), D <= 1.3), were prepared via reversible addition fragmentation chain transfer (RAFT) polymerization of protected maleimide functional RAFT agents. After deprotection of the furan-protected maleimide end groups, the polymers were photografted to o-methylbenzaldehyde functional NDs and characterized in detail via infrared (IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA). The grafting density decreases with increasing polymer chain length (6.9-3.8 mu mol g(-1)). Moreover, the binding of the glycopolymer functional NDs to the lectin Concanavalin A was demonstrated with a turbidity assay.