화학공학소재연구정보센터
Journal of Colloid and Interface Science, Vol.447, 152-158, 2015
Nanoparticles selectively immobilized onto large arrays of gold micro and nanostructures through surface chemical functionalizations
Latex nanoparticles (100 nm and 200 nm diameter) were precisely located onto the gold regions of micro and nanopatterned gold/silica substrates through surface chemical functionalizations. The gold patterns were selectively functionalized with alkylthiols bearing biotin or amine headgroups. This selective functionalization allowed the trapping of streptavidin- or carboxy-functionalized latex nanoparticles onto the gold structures with very little non-specific adsorption onto the surrounding silica. Quantitative data of nanoparticle capture on gold and silica, obtained through SEM image analysis, showed a one to two order of magnitude increase on gold with a similar low coverage on silica (non-specific adsorption) thanks to chemical functionalizations. Single nanoparticles were captured at the gap of dimer gold nanostructures. (C) 2014 Elsevier Inc. All rights reserved.