화학공학소재연구정보센터
Industrial & Engineering Chemistry Research, Vol.55, No.7, 1890-1901, 2016
Antifouling Coatings via Tethering of Hyperbranched Polyglycerols on Biomimetic Anchors
Hyperbranched polyglycerols (HPG) bearing terminal thiol moieties (HPG-SH) were synthesized via anionic ring -opening multibranching polymerization of glycidol from pentaerythritol and subsequent 1,1'-carbonyldiimidazole (CDI) coupling with cysteamine. Bioinspired (1) N-dopamine maleimide (DM), (2) tannic acid (TA), and (3) polydopamine (PDA) were employed to produce monolayer, multilayer, and polymeric anchors, respectively, on stainless-steel (SS) substrates. Postfunctionalization of the biomimetic anchor-modified SS surfaces was enacted by tethering of HPG-SH via Michael addition or thiol ene "click" reaction to confer surface hydrophilicity. The thickness and grafting density of HPG coatings could be controlled by tuning the degree of thiolation. In comparison to the pristine SS surface, the HPG-modified surfaces exhibited substantially reduced initial adhesion and inhibition of the biofilm formation of Gram-negative Pseudomonas sp. and Gram-positive Staphylococcus epidermidis. Qualitative and quantitative assays of settlement of the microalgae Amphora coffeaeformis further demonstrate the low fouling characteristics of the HPG-modified surfaces. Therefore, tethering of HPG coatings on biomimetic anchors provides an environmentally benign alternative to antifouling surfaces.