화학공학소재연구정보센터
Journal of Applied Electrochemistry, Vol.44, No.8, 953-962, 2014
Nanostructured manganese oxide-chitosan-based cholesterol sensor
Manganese oxide nano-rod (nano-MnO2) was prepared by simple oxidation method. To fabricate nanocomposite film (nano-MnO2/CT) onto glassy carbon electrode (GCE), nano-MnO2 was homogeneously dispersed in chitosan (CT). Cholesterol oxidase (ChOx) was immobilized onto nano-MnO2/CT by physisorption. Modified electrode was characterized by Fourier transform infrared, X-ray diffraction, cyclic voltammetry, scanning electron microscopy, transmission electron microscopy, and electrochemical impedance spectroscopy techniques. Prepared ChOx/nano-MnO2/CT/GCE bioelectrode exhibited 0.03-11.66 mM linearity and 2.07 x 10(-3) mM limit of detection for cholesterol. Biosensing characteristics of modified bioelectrode were superior than other electrodes modified with metal oxide nanoparticles, reported in the literature.