화학공학소재연구정보센터
Korean Journal of Materials Research, Vol.14, No.4, 287-292, April, 2004
CaO-SiO 2 -PEEK 생체복합체의 제조와 in-vitro 특성평가
Preparation of CaO-SiO 2 -PEEK bio-composites and in-vitro Evaluation
E-mail:
A bio-composites were prepared by mechanical mixing with bioactive sol-gel derived CaO?SiO 2 and organic PEEK for bone repairing hybrid materials. The composites were characterized by in-vitro test. A bonelike apatite was formed on the surface of all bio-composites in SBF test. The cell morphology and adhesion on the surface of the composites having below 30% PEEK were clearly observed in L929 cell experiment.
  1. Hench LL, Splinter RJ, Allen WC, Greenlee TK, J. Biomed. Res. Symp., 2, 117 (1971)
  2. Hench LL, J. Am. Ceram. Soc., 74, 1487 (1991)
  3. Kokubo T, Biomaterials, 12, 155 (1991)
  4. Lee SK, Koo KM, Lee MH, Lee HD, Lee BK, J. Kor. Ceram. Soc., 40(6), 566 (2003)
  5. Kokubo T, Acta Mater., 46(7), 2519 (1998)
  6. Oyane A, Nakanishi K, Kim HM, Miyaji F, Kokubo T, Soga N, Nakamura T, Biomaterials, 20, 79 (1999)
  7. Kokubo T, Thermochim. Acta, 280-281, 479 (1996)
  8. Zhang K, Wang Y, Hillmyer MA, Francis LF, Biomaterials, 25(13), 2489 (2004)
  9. Rhee SH, Biomaterials, 25, 1167 (2004)
  10. Miyata N, Fuke K, Chen Q, Kawashita M, Kokubo T, Nakamura T, Biomaterials, 23, 3033 (2002)
  11. Abu Baker MS, Cheang P, Khor KA, J. Mater. Proce. Tech., 89-90, 462 (1999)
  12. Ha SW, Hauert R, Ernst KH, Wintermantel E, Surf. & Coat. Tech., 96, 293 (1997)
  13. Tan KH, Chua CK, Leong KF, Cheah CM, Cheang P, Abu Baker MS, Cha SW, Biomaterials, 24, 3115 (2003)
  14. Kamitakahara M, Kawashita M, Kokubo T, Nakamura T, Biomaterials, 22, 3191 (2001)