화학공학소재연구정보센터
검색결과 : 36건
No. Article
1 Sulfur [F-18]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
Zheng QH, Xu HT, Wang H, Du WGH, Wang N, Xiong H, Gu Y, Noodleman L, Sharpless KB, Yang G, Wu P
Journal of the American Chemical Society, 143(10), 3753, 2021
2 Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
Kitamura S, Zheng QH, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW
Journal of the American Chemical Society, 142(25), 10899, 2020
3 A simple life-finding function and making connections
Sharpless KB
Chemical & Engineering News, 97(13), 37, 2019
4 Modular click chemistry libraries for functional screens using a diazotizing reagent
Meng GY, Guo TJ, Ma TC, Zhang J, Shen YC, Sharpless KB, Dong JJ
Nature, 574(7776), 86, 2019
5 "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
Mortenson DE, Brighty GJ, Plate L, Bare G, Chen WT, Li SH, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW
Journal of the American Chemical Society, 140(1), 200, 2018
6 SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
Liu ZL, Li J, Li SH, Li GC, Sharpless KB, Wu P
Journal of the American Chemical Society, 140(8), 2919, 2018
7 Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
Bourne Y, Sharpless KB, Taylor P, Marchot P
Journal of the American Chemical Society, 138(5), 1611, 2016
8 Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
Chen WT, Dong JJ, Plate L, Mortenson DE, Brighty GJ, Li SH, Liu Y, Galmozzi A, Lee PS, Hulce JJ, Cravatt BF, Saez E, Powers ET, Wilson IA, Sharpless KB, Kelly JW
Journal of the American Chemical Society, 138(23), 7353, 2016
9 A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
Baranczak A, Liu Y, Connelly S, Du WGH, Greiner ER, Genereux JC, Wiseman RL, Eisele YS, Bradbury NC, Dong JJ, Noodleman L, Sharpless KB, Wilson IA, Encalada SE, Kelly JW
Journal of the American Chemical Society, 137(23), 7404, 2015
10 Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
Grimster NP, Connelly S, Baranczak A, Dong JJ, Krasnova LB, Sharpless KB, Powers ET, Wilson IA, Kelly JW
Journal of the American Chemical Society, 135(15), 5656, 2013