검색결과 : 20건
No. | Article |
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1 |
Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc Staus DP, Hu HL, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G Nature, 579(7798), 297, 2020 |
2 |
Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor Suomivuori CM, Latorraca NR, Wingler LM, Eismann S, King MC, Kleinhenz ALW, Skiba MA, Staus DP, Kruse AC, Lefkowitz RJ, Dror RO Science, 367(6480), 881, 2020 |
3 |
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR Wingler LM, Skiba MA, McMahon C, Staus DP, Kleinhenz ALW, Suomivuori CM, Latorraca NR, Dror RO, Lefkowitz RJ, Kruse AC Science, 367(6480), 888, 2020 |
4 |
Mechanism of beta(2)AR regulation by an intracellular positive allosteric modulator Liu XY, Masoudi A, Kahsai AW, Huang LY, Pani B, Staus DP, Shim PJ, Hirata K, Simhal RK, Schwalb AM, Rambarat PK, Ahn S, Lefkowitz RJ, Kobilka B Science, 364(6447), 1283, 2019 |
5 |
Mechanism of intracellular allosteric beta(2)AR antagonist revealed by X-ray crystal structure Liu XY, Ahn S, Kahsai AW, Meng KC, Latorraca NR, Pani B, Venkatakrishnan AJ, Masoudi A, Weis WI, Dror RO, Chen X, Lefkowitz RJ, Kobilka BK Nature, 548(7668), 480, 2017 |
6 |
Alfred Goodman Gilman (1941-2015) OBITUARY Lefkowitz RJ Nature, 529(7586), 284, 2016 |
7 |
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, Kobilka BK, Costa T, Lefkowitz RJ Nature, 535(7612), 448, 2016 |
8 |
Visualization of arrestin recruitment by a G-protein-coupled receptor Shukla AK, Westfield GH, Xiao KH, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, Chen X, Hanna R, Choi MJ, Yao XJ, Klink BU, Kahsai AW, Sidhu SS, Koide S, Penczek PA, Kossiakoff AA, Woods VL, Kobilka BK, Skiniotis G, Lefkowitz RJ Nature, 512(7513), 218, 2014 |
9 |
A stress response pathway regulates DNA damage through beta(2)-adrenoreceptors and beta-arrestin-1 Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao KH, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ Nature, 477(7364), 349, 2011 |
10 |
beta-arrestin-dependent formation of beta(2) adrenergic receptor Src protein kinase complexes Luttrell LM, Ferguson SSG, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, Lin FT, Kawakatsu H, Owada K, Luttrell DK, Caron MG, Lefkowitz RJ Science, 283(5402), 655, 1999 |