화학공학소재연구정보센터
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No. Article
1 An umbrella approach to test lung cancer therapies
Drilon A, Hellmann MD
Nature, 583(7818), 688, 2020
2 An umbrella approach to test lung cancer therapies
Drilon A, Hellmann MD
Nature, 583(7818), 688, 2020
3 Neoantigen-directed immune escape in lung cancer evolution
Rosenthal R, Cadieux EL, Salgado R, Al Bakir M, Moore DA, Hiley CT, Lund T, Tanic M, Reading JL, Joshi K, Henry JY, Ghorani E, Wilson GA, Birkbak NJ, Jamal-Hanjani M, Veeriah S, Szallasi Z, Loi S, Hellmann MD, Feber A, Chain B, Herrero J, Quezada SA, Demeulemeester J, Van Loo P, Beck S, McGranahan N, Swanton C, Swanton C, Jamal-Hanjani M, Veeriah S, Czyzewska-Khan J, Johnson D, Laycock J, Rosenthal R, Gorman P, Hynds RE, Wilson G, Birkbak NJ, Watkins TBK, McGranahan N, Escudero M, Stewart A, Loo P, Rowan A, Hiley C, Abbosh C, Goldman J, Stone RK, Denner T, Ward S, Nye E, Joshi K, Aissa A, Wong YNS, Georgiou A, Quezada S, Hartley JA, Lowe HL, Herrero J, Lawrence D, Hayward M, Panagiotopoulos N, Falzon M, Borg E, Marafioti T, Janes SM, Forster M, Ahmad T, Lee SM, Papadatos-Pastos D, Carnell D, Mendes R, George J, Ahmed A, Taylor M, Choudhary J, Summers Y, Califano R, Taylor P, Shah R, Krysiak P, Rammohan K, Fontaine E, Booton R, Evison M, Crosbie P, Moss S, Joseph L, Bishop P, Quinn AM, Doran H, Leek A, Harrison P, Moore K, Waddington R, Novasio J, Blackhall F, Rogan J, Smith E, Dive C, Tugwood J, Brady G, Rothwell DG, Pierce J, Gulati S, Naidu B, Langman G, Trotter S, Bancroft H, Kerr A, Kadiri S, Middleton G, Djearaman M, Fennell D, Shaw JA, Le Quesne J, Moore DA, Nakas A, Rathinam S, Monteiro W, Marshall H, Nelson L, Riley J, Primrose L, Martinson L, Anand G, Khan S, Nicolson M, Kerr K, Palmer S, Remmen H, Miller J, Buchan K, Chetty M, Gomersall L, Lester J, Morgan F, Adams H, Davies H, Kornaszewska M, Attanoos R, Lock S, MacKenzie M, Wilcox M, Bell H, Hackshaw A, Ngai Y, Smith S, Gower N, Ottensmeier C, Chee S, Johnson B, Alzetani A, Shaw E, Lim E, De Sousa P, Barbosa MT, Bowman A, Jordan S, Rice A, Raubenheimer H, Bhayani H, Hamilton M, Mensah N, Ambrose L, Devaraj A, Chavan H, Nicholson AG, Lau K, Sheaff M, Schmid P, Conibear J, Ezhil V, Prakash V, Russell P, Light T, Horey T, Danson S, Bury J, Edwards J, Hill J, Matthews S, Kitsanta Y, Suvarna K, Fisher P, Shackcloth M, Gosney J, Feeney S, Asante-Siaw J, Ryanna K, Dawson A, Tuffail M, Bajaj A, Brozik J, Walter H, Carey N, Price G, Gilbert K, Webb J, Patel A, Chaturvedi A, Granato F, Baker K, Carter M, Priest L, Krebs MG, Lindsay C, Gomes F, Chemie F, George R, Patrini D, Khiroya R, Shaw P, Skrzypski M, Sunderland MW, Reading JL, Beastall C, Mangal N, Peggs K, Lim E, Al-Bakir M, Navani N, Scarci M, Ensell L, Biswas D, Salgado R, Razaq M, Nicod J, Beck S, Lopez S, Huebner A, Dietzen M, Mourikis T, Adefila-Ideozu T, Begum S, Klein H, Mani A, Carvalho S, Kaniu D, Realingo C, Malima M, Booth S, Lim L, Rao J, Tenconi S, Socci L, Kibutu F, Agyemang M, Young R, Blyth KG, Dick C, Kirk A, Kidd A
Nature, 567(7749), 479, 2019
4 TOX is a critical regulator of tumour-specific T cell differentiation
Scott AC, Dundar F, Zumbo P, Chandran SS, Klebanoff CA, Shakiba M, Trivedi P, Menocal L, Appleby H, Camara S, Zamarin D, Walther T, Snyder A, Femia MR, Comen EA, Wen HY, Hellmann MD, Anandasabapathy N, Liu Y, Altorki NK, Lauer P, Levy O, Glickman MS, Kaye J, Betel D, Philip M, Schietinger A
Nature, 571(7764), 270, 2019
5 Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
Routy B, Le Chatelier E, Derosa L, Duong CPM, Alou MT, Daillere R, Fluckiger A, Messaoudene M, Rauber C, Roberti MP, Fidelle M, Flament C, Poirier-Colame V, Opolon P, Klein C, Iribarren K, Mondragon L, Jacquelot N, Qu B, Ferrere G, Clemenson C, Mezquita L, Masip JR, Naltet C, Brosseau S, Kaderbhai C, Richard C, Rizvi H, Levenez F, Galleron N, Quinquis B, Pons N, Ryffel B, Minard-Colin V, Gonin P, Soria JC, Deutsch E, Loriot Y, Ghiringhelli F, Zalcman G, Goldwasser F, Escudier B, Hellmann MD, Eggermont A, Raoult D, Albiges L, Kroemer G, Zitvogel L
Science, 359(6371), 91, 2018
6 Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma
Miao D, Margolis CA, Gao WH, Voss MH, Li W, Martini DJ, Norton C, Bosse D, Wankowicz SM, Cullen D, Horak C, Wind-Rotolo M, Tracy A, Giannakis M, Hodi FS, Drake CG, Ball MW, Allaf ME, Snyder A, Hellmann MD, Ho T, Motzer RJ, Signoretti S, Kaelin WG, Choueiri TK, Van Allen EM
Science, 359(6377), 801, 2018
7 Chromatin states define tumour-specific T cell dysfunction and reprogramming
Philip M, Fairchild L, Sun L, Horste EL, Amara SC, Shakiba M, Scott AC, Viale A, Lauer P, Erghoub TM, Hellmann MD, Wolchok JD, Leslie CS, Schietinger A
Nature, 545(7655), 452, 2017
8 A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
Luksza M, Riaz N, Makarov V, Balachandran VP, Hellmann MD, Solovyov A, Rizvi NA, Merghoub T, Levine AJ, Chan TA, Wolchok JD, Greenbaum BD
Nature, 551(7681), 517, 2017
9 Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
McGranahan N, Furness AJS, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TBK, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao DN, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C
Science, 351(6280), 1463, 2016
10 Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan JD, Wong P, Ho TS, Miller ML, Rekhtman N, Moreira AL, Ibrahim F, Bruggeman C, Gasmi B, Zappasodi R, Maeda Y, Sander C, Garon EB, Merghoub T, Wolchok JD, Schumacher TN, Chan TA
Science, 348(6230), 124, 2015