Journal of Fermentation and Bioengineering
Volume 83, Issue 1, 1997, Pages 59-63
Regular paperColominic acid production from Escherichia coli in a fed-batch culture under the control of ammonium ions using an FIA system
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Cited by (10)
An efficient and large-scale preparation process for polysialic acid by Escherichia coli CCTCC M208088
2010, Biochemical Engineering JournalCitation Excerpt :Previously, we demonstrated that the biosynthesis of the PSA was inhibited as sorbitol level higher than 40 g/L [15]. Furthermore, it was observed that ammonia concentration could severely affect the cell growth and PSA production with E. coli, and a flow injection analysis (FIA) system was employed by Honda et al. to monitor and control the ammonia in an optimal level of 0.3 g/L, which resulted in a maximum PSA production of 1900 mg/L [16]. Hitherto, few reports on the isolation of PSA from the fermentation broth have been published impacting the industrial production of PSA.
Continuous production of sialyllactose from colominic acid using a membrane reactor
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2012, International Journal of PharmTech ResearchEnhancement of polysialic acid yield by reducing initial phosphate and feeding ammonia water to Escherichia coli CCTCC M208088
2010, Biotechnology and Bioprocess Engineering
Copyright © 1997 Published by Elsevier B.V.