화학공학소재연구정보센터
  • 최근 나노입자의 toxicology와 clinical potential
  •  11김수현  (2013/12/06)추천1   조회수1107
  • In recent years, nanoparticles (NPs) have increasingly found practical applications in technology, research and medicine. The small particle size coupled to their unique chemical and physical properties is thought to underlie their exploitable biomedical activities. Here, we review current toxicity studies of NPs with clinical potential. Mechanisms of cytotoxicity are discussed and the problem of extrapolating knowledge gained from cell-based studies into a human scenario is highlighted. The so-called ‘proof-of-principle’ approach, whereby ultra-high NP concentrations are used to ensure cytotoxicity, is evaluated on the basis of two considerations; firstly, from a scientific perspective, the concentrations used are in no way related to the actual doses required which, in many instances, discourages further vital investigations. Secondly, these inaccurate results cast doubt on the science of nanomedicine and thus, quite dangerously, encourage unnecessary alarm in the public. In this context, the discrepancies between in vitro and in vivo results are described along with the need for a unifying protocol for reliable and realistic toxicity reports.
전체덧글7 
  •  Orion  (2022-12-13 19:05:17) +덧글답변   공감0   비공감0  
  • Sincerity dictates that this website called how-to-create-an-electronic-signature-without-a-pdf-editor is one of mine. Sincerely, I've never seen anything like this. No drawbacks at all!
  •  Orion  (2022-12-15 21:03:41) +덧글답변   공감0   비공감0  
  • Alot of the content on this site is about signatures. I have learned a significant difference from the content on www.airslate.com/product/contract-negotiation. It is good, check it out.
  •  Orion  (2022-12-21 18:32:52) +덧글답변   공감0   비공감0  
  • Truly, this article is really one of the very best in the history of articles. I am a antique ’Article’ collector and I sometimes read some new articles if I find them interesting. And I found this one pretty fascinating and it should go into my collection. Very good work! Wazdan
  •  Orion  (2022-12-22 19:05:03) +덧글답변   공감0   비공감0  
  • This is a great post. I like this topic.This site has lots of advantage.I found many interesting things from this site. It helps me in many ways.Thanks for posting this again. Math Operations
  •  Orion  (2022-12-23 01:39:01) +덧글답변   공감0   비공감0  
  • Great tips and very easy to understand. This will definitely be very useful for me when I get a chance to start my blog. norwich stairlifts
  •  Orion  (2022-12-24 22:31:33) +덧글답변   공감0   비공감0  
  • That is very helpful for increasing my knowledge in this field. beauty salon sheringham
  •  Orion  (2022-12-28 19:37:20) +덧글답변   공감0   비공감0  
  • This post is good enough to make somebody understand this amazing thing, and I’m sure everyone will appreciate this interesting things. seguridad cancun
덧글쓰기 * 회원 로그인하셔야만 덧글쓰기가 가능합니다.*     작성자